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What is the pathology of periodontal disease?

List specific toxins or other chemicals involved in the making of periodontal disease

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One Response to “What is the pathology of periodontal disease?”
  1. Periodontal disease is inflammation of some or all of the tooth’s support structures (gingiva, cementum, periodontal ligament, and alveolar bone). When compared to gingivitis, periodontitis indicates bone loss.

    Periodontal disease is caused by bacteria. Initially a pellicle forms on the clean tooth. This pellicle attracts aerobic gram positive bacteria (mostly actinomyces and strepococci). Soon more bacteria adhere forming plaque. With in days the plaque thickens, underlying bacteria run out of oxygen and anaerobic motile rods and spirochetes begin to populate the subgingival area. Endotoxins released by the anaerobic bacteria cause tissue destruction and bone loss.


    Grade 1 Inflammation
    Grade 2 Inflammation, edema, gingival bleeding upon probing
    Grade 3 Inflammation, edema, gingival bleeding upon probing, pustular discharge — slight to moderate bone loss
    Grade 4 Inflammation, edema, gingival bleeding upon probing, pustular discharge, mobility — severe bone loss


    Marked bone loss
    secondary to
    periodontal disease
    Gingivitis – streptococcus and actinomyces species

    Periodontitis – pigmented and non pigmented Bacteroides (Porphyromonas Gingivalis, Prevoltella sp., Bacteroides sp.), Fusobacterium

    Peptostreptococcus sp., actinomyces, and porphyromonas SP.

    Diet: soft diet promotes periodontal disease through accumulation of plaque.

    Risk Factors
    Smoking, genetics, pregnancy and puberty;
    poor nutrition state; diabetes,stress,clenching and teeth grinding; medications, untreated gingivitis; systemic diseases such as Rheumatoid arthritis which interfere with th eimmune system.

    Differential Diagnosis – phemphigus, lupus, oral neoplasia, stomatitis

    CBC/CHEM/U/A – N/A

    The ultimate goal of periodontal therapy is to control plaque. A willing patient and client who is able to provide home care are important considerations in creating a therapy plan.

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